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Tcris (Amorolfine 0.25%) Cream 0.25% w/w 30g


Tcris (Amorolfine 0.25%) Cream 0.25% w/w 30g

Tcris (Amorolfine) Cream 0.25% 30g

  Generic

This product has been discontinued, but we do have alternatives below.

Product Name
Tcris (Amorolfine 0.25%) Cream 0.25% w/w 30g
Also known as Loceryl
Active Ingredient
Amorolfine
Manufacturer
Brinton Pharmaceuticals
Product Type
Antifungal
Product expiry date we are currently shipping
Discontinued, no stock

Tcris cream 0.25% contains amorolfine, a broad spectrum antifungal that is used as a topical treatment for fungal infections of the nails (onychomycosis).  

Tcris general information

What is Tcris used for?

Tcris cream 0.25% is a topical treatment for fungal infection of the nails, (onychomycosis), that is caused by fungi belonging to the dermatophytes, yeasts or moulds and for infections where the growing part of the nail plate (the matrix) is not involved.  Tcris cream 0.25% is effective against fungal infections due to dermatophytes like Tinea and Trichophyton that cause tinea of the nails known as tinea unguium as well as other common skin infections known as ringworm like tinea of the body (tinea pedis), foot (tinea corporis) and groin (tinea cruris); also against the yeast Candida albicans that causes candidiasis or thrush of the nail, and the mould Scopulariopsis.  Symptoms of onychomycosis include, white/yellow discolouration, crumbling and lifting of the nail, and can cause destruction of the nail if left untreated.  Tcris cream 0.25% relieves symptoms of onychomycosis and clears the fungal infection.

How does Tcris work?

Tcris cream 0.25% contains amorolfine, a broad spectrum antifungal that is used in solution as a topical application for treatment of onychomycosis (fungal infections of the nails) due to a range of fungi, including dermatophytes, yeasts and moulds.  Amorolfine in Tcris cream 0.25% works by blocking sterol biosynthesis, which is essential for the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells.  This action of amorolfine in Tcris cream 0.25% results in a reduced ergosterol content and abnormal sterol production, altering the structure of the fungal cell membrane, which prevents the fungus from growing and kills the fungus, (fungistatic or fungicidal). 

What does Tcris contain?

Tcris cream 0.25% contains the active ingredient amorolfine, a topical broad spectrum antifungal that is used in solution to treat onychomycosis.  Each pack contains 0.25ml Tcris cream, 60 isopropyl cleansing swabs, 30 nail files and 10 re-usable spatulas. 

Treating onychomycosis (fungal infection of the nails) with Tcris

Tcris cream 0.25% contains amorolfine, a broad spectrum antifungal that is used as a topical treatment for fungal infections of the nails (onychomycosis).  Tcris cream 0.25% is effective against fungal infections due to dermatophytes like Tinea and Trichophyton that cause tinea of the nails known as tinea unguium; also against the yeast Candida albicans that causes candidiasis or thrush of the nail; and the mould Scopulariopsis.  Amorolfine in Tcris cream 0.25% works by blocking sterol biosynthesis, which is essential for the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells.  This action of amorolfine in Tcris cream 0.25% results in altered structure of the fungal cell membrane, which prevents the fungus from growing and kills the fungus, (fungistatic or fungicidal).  Tcris cream 0.25% relieves symptoms of onychomycosis, which include white/yellow discolouration, crumbling and lifting of the nail, and destruction of the nail if left untreated, and clears the fungal infection.

What are the side effects of Tcris?

The most commonly reported side effects when using Tcris cream 0.25% include burning sensation, itching and erythema (redness) at the site of application.

When should Tcris not be used?

You should not use Tcris cream 0.25% if you:

  • are allergic to amorolfine or any ingredients in Tcris
  • are pregnant or are breastfeeding, without discussion with your doctor.

How should Tcris be used?

You should apply your Tcris cream 0.25% once or twice weekly.  Before application of Tcris cream 0.25%, you should file down the infected areas of the nail (particularly the nail surfaces) as thoroughly as possible and then clean the nail surface.  Apply to the entire surface of the infected nail and repeat for each infected nail.  Apply your Tcris cream 0.25% only to finger nails and toe nails, avoid the surrounding skin and, do not use cosmetic lacquers, artificial nails, or occlusive dressings while you are using Tcris cream 0.25%.  You should continue to use your Tcris cream 0.25% until the fungal infection has cleared up and the nail is regenerated, which usually takes between 6-12 months as nails grow very slowly by approximately 2mm per month. 

How long should you use Tcris?

You should continue to use your Tcris cream 0.25% until the fungal infection has cleared up and the nail is regenerated, which usually takes between 6-12 months as nails grow very slowly by approximately 2mm per month. 

Missed dose of Tcris

If you miss a dose of Tcris cream 0.25% apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose.  Do not apply a double dose.

How should Tcris be stored?

You should store your Tcris cream 0.25% below 25°C in a cool dry place.  

All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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