FREE SHIPPING To United States
Free Shipping To USA!
All products and operations are monitored by highly skilled,
registered pharmacists
in order to ensure a high quality service!
Your Country: ?
Your Currency: ?
Questran Lite (Cholestyramine Resin 4g) 50 Sachets/Pack


Questran Lite (Cholestyramine Resin 4g) 50 Sachets/Pack

Questran Lite (Cholestyramine) Sachets

This product has been discontinued and we currently do not have an alternative available at this time.

Product Name
Questran Lite (Cholestyramine Resin 4g) 50 Sachets/Pack
Active Ingredient
Cholestyramine Resin
Manufacturer
Aspen
Product Type
Cholesterol-lowering (bile acid sequestrant)
Product expiry date we are currently shipping
Discontinued, no stock

Questran Lite contains cholestyramine, an anion exchange resin that is used as a bile acid sequestrant to treat hypercholesterolemia by lowering cholesterol, relieve pruritus associated with partial biliary obstruction, and relieve chronic diarrhoea in cholerrhoeic enteropathy. 

Questran Lite general information

What is Questran Lite used for?

Questran Lite is used to lower high levels of blood cholesterol in people with primary hypercholesterolemia, which includes elevated low density lipoproteins (LDL “bad cholesterol”) and other fats (triglycerides) to reduce health risks associated with coronary heart disease (CHD), including heart attack and angina that can be caused by high cholesterol.  There are usually no symptoms for high cholesterol, which is often related to lifestyle, including high-fat diet and lack of exercise and Questran Lite should be used in conjunction with improved diet and exercise.  Questran Lite is also used to treat pruritus (itching) associated with partially blocked bile flow, known as partial biliary obstruction, which usually also results in elevated blood cholesterol levels.  Treatment to relieve pruritis may also reduce blood cholesterol, but is not always the case.  Questran Lite is also used to treat cholerrhoeic enteropathy, following surgery of the small bowel (ileal resection) or due to ileal disease such as Crohn’s disease, causing inflammation, to provide relief of diarrhoea caused by the surgery or disease. 

How does Questran Lite work?

Questran Lite contains cholestyramine, the chloride salt of a basic anion exchange resin that is used to lower cholesterol by combining with bile salts in the intestines, forming an insoluble complex, which is excreted in the faeces.  The enterohepatic circulation is the movement of bile acid molecules from the liver to the small intestine and back to the liver.  Bile acids are synthesized from cholesterol in hepatocytes (liver cells) and conjugated to form bile salts, which are carried in the bile to concentrate in the gall bladder between periods when not needed for digestion.  They are then carried down the bile duct to the small intestine where they play an important role in the digestion and absorption of lipids from the diet; also absorption of lipid soluble vitamins such as the vitamins A, D, E, and K from the small intestine.  Finally bile salts are recycled and reabsorbed into the blood, returning to the liver via the portal vein and back to the gall bladder.  Normally very small amounts of bile salts are found remaining in the blood.  Cholestyramine in Questran Lite works by binding to the bile salts preventing them returning to the enterohepatic circulation.  This removal of bile salts from the enterohepatic circulation prevents their reabsorption and recycling; the overall effect of which is increased synthesis of more bile acids from cholesterol and decreased levels of blood cholesterol and low density lipoprotein “bad cholesterol”.  Although there is increased synthesis of cholesterol in the liver to produce more bile acids there is a net reduction in circulating cholesterol.  Cholestyramine in Questran Lite is insoluble in water and is not absorbed from the gastrointestinal tract nor is it affected by digestive enzymes and is excreted bound to bile salts unchanged.  Questran Lite works by the same mechanism of action, as a bile acid sequestrant, to lower cholesterol in hypercholesterolemia; also to provide relieve from pruritis due to partial biliary obstruction, and relief of diarrhoea due to ileal surgery or disease.

What does Questran Lite contain?

Questran Lite contains the active ingredient cholestyramine, used to reduce cholesterol levels in hypercholesterolemia and provide relieve from pruritis due to partial biliary obstruction, also to provide relief of diarrhoea due to ileal surgery or disease.  Cholestyramine in Questran Lite is a sugar free formulation containing 4g of cholestyramine per 4.7g of Questran Lite powder.  It also contains Kelcoloid LVF, Xanthan gum, natural and artificial orange juice flavour, aspartame, citric acid and silicon dioxide.

Treating high cholesterol with Questran Lite

Questran Lite contains cholestyramine, a basic anion exchange resin that is used to lower high levels of blood cholesterol in people with primary hypercholesterolemia, to reduce health risks associated with coronary heart disease (CHD), including heart attack and angina that can be caused by high cholesterol.  There are usually no symptoms for high cholesterol, which is often related to lifestyle, including high-fat diet and lack of exercise and Questran Lite should be used in conjunction with improved diet and exercise.  Cholestyramine in Questran Lite works by combining with bile salts in the intestines, forming an insoluble complex, which is excreted in the faeces.  Bile acids are synthesized from cholesterol in hepatocytes (liver cells) and conjugated to form bile salts, which are carried in the bile to concentrate in the gall bladder between periods when not needed for digestion.  They are then carried down the bile duct to the small intestine where they play an important role in the digestion and absorption of lipids from the diet; also absorption of lipid soluble vitamins such as the vitamins A, D, E, and K from the small intestine.  Finally bile salts are recycled and reabsorbed into the blood, returning to the liver via the portal vein and back to the gall bladder.  This is known as the enterohepatic circulation.  Removal of bile salts from the enterohepatic circulation prevents their reabsorption and recycling; the overall effect of which is increased synthesis of more bile acids from cholesterol and decreased levels of blood cholesterol and low density lipoprotein “bad cholesterol”.  Although there is increased synthesis of cholesterol in the liver to produce more bile acids there is a net reduction in circulating cholesterol. 

Questran Lite for partial biliary obstruction

Questran Lite contains cholestyramine, a basic anion exchange resin that is used to relieve pruritus (itching) associated with flow of bile being partially blocked and known as partial biliary obstruction, which usually also results in elevated blood cholesterol levels.  Itching or pruritus due to obstruction of the bile ducts is thought to be the effect of accumulation of excess bile salts in the skin and sensitising nerve cells to the skin and is associated with many liver diseases.  Obstruction of the bile ducts can be due to many causes but more usually due to gall stones, which are caused by crystallisation of bile salts and bile pigments such as bilirubin, a breakdown product of red blood cells.  Cholestyramine in Questran Lite works by combining with bile salts in the intestines, forming an insoluble complex, which is excreted in the faeces.  Bile acids are synthesized from cholesterol in hepatocytes (liver cells) and conjugated to form bile salts, which are carried in the bile to concentrate in the gall bladder between periods when not needed for digestion.  They are then carried down the bile duct to the small intestine where they play an important role in the digestion and absorption of lipids from the diet.  Bile salts are finally recycled and reabsorbed into the blood, returning to the liver via the portal vein and back to the gall bladder.  This is known as the enterohepatic circulation, which includes the bile ducts.  Removal of bile salts from the enterohepatic circulation prevents their reabsorption and recycling; the overall effect of which is increased synthesis of more bile acids from cholesterol and improved flow through the enterohepatic circulation, which helps prevent build-up of bile salts and pigments.  

Questran Lite for cholerrhoeic enteropathy

Questran Lite contains cholestyramine, a basic anion exchange resin that is used to treat cholerrhoeic enteropathy that occurs following surgery of the small bowel (ileal resection) or caused by ileal disease such as Crohn’s disease, to provide relief of diarrhoea caused by the surgery or disease.  Cholerrhoeic enteropathy, which is chronic diarrhoea due to inflammation of the small intestine, is caused by reduced absorption of bile acids in the ileum of the small intestine.  Cholestyramine in Questran Lite works by combining with bile salts in the intestines, forming an insoluble complex, which is excreted in the faeces.  Bile acids are synthesized from cholesterol in hepatocytes (liver cells) and conjugated to form bile salts, which are carried in the bile to concentrate in the gall bladder between periods when not needed for digestion.  They are then carried down the bile duct to the small intestine where they play an important role in the digestion and absorption of lipids from the diet.  Bile salts are finally recycled and reabsorbed into the blood, returning to the liver via the portal vein and back to the gall bladder.  This is known as the enterohepatic circulation, which includes the bile ducts.  Removal of bile salts from the enterohepatic circulation prevents their reabsorption and recycling, which helps prevent build-up of bile salts and helps to relieve chronic diarrhoea associated with cholerrhoeic enteropathy. 

What are the side effects of Questran Lite?

The most commonly reported side effects when taking Questran Lite include constipation, which may be severe and occasionally accompanied by faecal impaction and/or haemorrhoids with or without bleeding; abdominal discomfort (pain and distension), flatulence, nausea, vomiting, heartburn, diarrhoea, anorexia, dyspepsia and steatorrhoea (fatty stools); rash and irritation of the skin, tongue and perianal area;

When should Questran Lite not be used?

You should not use Questran Lite if you:

  • are allergic to cholestyramine or any ingredients in Questran Lite
  • are pregnant or are breastfeeding, without discussion with your doctor
  • have liver disease including jaundice
  • have complete biliary obstruction where no bile is secreted into the intestine
  • have phenylketonuria as cholestyramine preparation contains phenylalanine
  • have blood clotting problems associated with vitamin K deficiency, cholestyramine can cause increased bleeding
  • have problems with constipation
  • have too much chloride in the blood (hyperchloraemic acidosis)
  • are taking medicines that interact with Questran Lite including the anti-inflammatory phenylbutazone, the anticoagulant warfarin, the diuretic chlorothiazide (acidic), the antibiotic tetracycline, the barbiturate phenobarbitone, thyroid and thyroxine preparations, digitalis for heart failure and inorganic iron, estrogens

Warning:

Discontinuation of cholestyramine resin could be hazardous to health if a potentially toxic drug such as digitalis had been titrated to a maintenance level while the patient was taking cholestyramine resin.

What medications interact with Questran Lite?

Several medications interact with Questran Lite and should either not be taken while you are taking Questran Lite or only after discussion and instruction from your doctor:

  • Drugs that may have delayed absorption due to binding to Questran Lite: the anti-inflammatory phenylbutazone, the anticoagulant warfarin, the diuretic chlorothiazide (acidic), the antibiotic tetracycline, the barbiturate phenobarbitone, thyroid and thyroxine preparations, digitalis for heart failure and inorganic iron
  • Drugs that are affected by Questran Lite: estrogens

How should Questran Lite be taken?

You should take your Questran Lite only when mixed with a liquid and never in dry form.  You should take Questran Lite once daily morning or evening with or without food.  The dose you take depends on what you are being treated for and your doctor’s recommendation.  If you are taking other medications they should be taken at least one hour before taking your Questran Lite.  You should continue to take your Questran Lite for as long as recommended by your doctor, which may be for several weeks or more.

Instructions for use:

  1. Add the contents of the 4g sachet to 100-150ml of water, fruit juice or a thin soup.
  2. Mix immediately by stirring vigorously and continue to stir until the mixture forms an even suspension (the powder will not dissolve).
  3. Drink the entire mixture immediately.
  4. Rinse the container and drink the rinse to ensure that you have taken the full dose.

How long should you take Questran Lite?

You should continue to take your Questran Lite for as long as recommended by your doctor, which may be for several weeks or more.

Missed dose of Questran Lite

If you miss a dose of Questran Lite take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Questran Lite be stored?

You should store your Questran Lite below 25°C in a cool dry place. 

 

All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
What is this ?
Please select your country to display all the products we are able to supply to you.
What is this ?
Select the currency that you would like to display the prices in. This will be the currency that appears on your credit card statement.
 

This website uses cookies. View our policy and select your preferences here