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APO-Perindopril (Perindopril 4mg) 30 Tablets/Pack


APO-Perindopril (Perindopril 4mg) 30 Tablets/Pack

APO-Perindopril 4mg

  Generic

This product has been discontinued and we currently do not have an alternative available at this time.

Product Name
APO-Perindopril (Perindopril 4mg) 30 Tablets/Pack
Also known as Coversyl
Active Ingredient
Perindopril
Manufacturer
Apotex
Product Type
Antihypertensive, ACE inhibitor
Product expiry date we are currently shipping
Discontinued, no stock

Apo-Perindopril tablets 4mg contain perindopril, an Angiotensin Converting Enzyme (ACE) inhibitor, used to treat hypertension and congestive heart failure, by widening blood vessels and lowering blood pressure.

Apo-Perindopril general information

What is Apo-Perindopril used for?

Apo-Perindopril tablets 4mg are used to treat essential hypertension, which is high blood pressure when at rest, by lowering blood pressure to normal resting levels.  Although there are usually no symptoms of high blood pressure, lowering high blood pressure reduces risk of stroke, heart attack and end organ damage such as kidney disease.  Apo-Perindopril tablets 4mg are also used to treat symptomatic congestive heart failure, in addition to treatment with digitalis and/or a diuretic, by helping weakened heart muscles pump more efficiently and reducing feelings of breathlessness on exertion.  Apo-Perindopril tablets 4mg are also used to reduce the risk of cardiac events, such as heart attack or cardiac arrest, in patients with stable coronary artery disease, where the blood supply to the heart is reduced or blocked, and who have already had a heart attack and/or revascularisation surgery.  Apo-Perindopril tablets 4mg can be used alone as monotherapy or with a diuretic, which helps get rid of excess water that is retained in body tissues and can cause swelling (oedema). 

How does Apo-Perindopril work?

Apo-Perindopril tablets 4mg contain perindopril a specific and long-acting Angiotensin Converting Enzyme (ACE) inhibitor that prevents the formation of angiotensin II, a hormone that has several actions involved in regulating blood pressure, which is the force needed to pump blood around the body.  Angiotensin II causes salt and water retention by the kidneys, and causes blood vessels to constrict (narrow); this increases blood volume while at the same time reducing blood vessel volume, which increases blood pressure.  Perindopril in Apo-Perindopril tablets 4mg inhibits the conversion of angiotensin II from angiotensin I, which allows blood vessels to relax and widen, reducing the force needed by the heart to pump blood around the body, reducing its workload and lowering blood pressure.  This also helps weakened heart muscle, such as in congestive heart failure, to work more efficiently and reduces symptoms of breathlessness on exertion.  Perindopril in Apo-Perindopril tablets 4mg is rapidly absorbed into the blood and rapidly converted to the active form, perindoprilat; it is effective within one hour and is effective for 24 hours, so that you need only take one tablet a day.

What does Apo-Perindopril contain?

Apo-Perindopril tablets 4mg contains the active ingredient perindopril erbumine an Angiotensin Converting Enzyme (ACE) inhibitor that is used to treat hypertension and congestive heart failure.  They also contain lactose anhydrous and magnesium stearate.

Treating hypertension (high blood pressure) with Apo-Perindopril

Apo-Perindopril tablets 4mg contain perindopril, an Angiotensin Converting Enzyme (ACE) inhibitor that is used to treat primary hypertension in people with high blood pressure when at rest, who are at increased risk of cardiovascular disease, including stroke and heart attack.  Perindopril in Apo-Perindopril tablets 4mg. inhibits the formation of angiotensin II, a hormone that has several actions involved in regulating blood pressure, which is the force needed to pump blood around the body.  Apo-Perindopril tablets 4mg  causes blood vessels to relax and widen, reducing the force needed by the heart to pump blood around the body, reducing its workload and lowering blood pressure.  Although there are usually no symptoms of high blood pressure, lowering blood pressure using Apo-Perindopril tablets 4mg reduces the risk of complications such as stroke and heart attack, due to high blood pressure.  

Apo-Perindopril for congestive heart failure

Apo-Perindopril tablets 4mg contain perindopril, an Angiotensin Converting Enzyme (ACE) inhibitor that is used to widen blood vessels and reduce the force needed for the heart to pump blood around the body.  This helps weakened heart muscle, such as in congestive heart failure, to work more efficiently and reduces symptoms of breathlessness on exertion.  You may also be prescribed a diuretic to help get rid of excess water that is retained in body tissues and can cause swelling (oedema), as a result of congestive heart failure.

What are the side effects of Apo-Perindopril?

The most commonly reported side effects when taking Apo-Perindopril tablets 4mg include dizziness, headache, cough, hypotension, vision disturbance, tinnitus, rash, nausea, diarrhoea, muscle cramps, fatigue.

When should Apo-Perindopril not be used?

You should not use Apo-Perindopril tablets 4mg if you:

  • are allergic to perindopril or any other ACE inhibitor or any or any ingredients in Apo-Perindopril
  • are pregnant or are breastfeeding
  • have kidney or liver disease
  • have diabetes, without careful monitoring of blood glucose levels
  • have hereditary or idiopathic angioedema (rapid swelling under the skin)
  • are taking potassium tablets or potassium-containing salt substitutes
  • are taking medications that interact with Apo-Perindopril, including, potassium-sparing diuretics like spironolactone, lithium for mood disorders, antidiabetics like insulin, non-steroidal anti-inflammatory medicines (NSAIDs) like diclofenac or ibuprofen, lithium for mood disorders, non-steroidal anti-inflammatory medicines (NSAIDs), other antihypertensives like methyldopa, calcium entry blockers or beta blockers

What medications interact with Apo-Perindopril?

Several medications interact with Apo-Perindopril tablets 4mg and should either not be taken while you are taking Apo-Perindopril or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction with Apo-Perindopril: potassium-sparing diuretics like spironolactone may cause low blood calcium, non-steroidal anti-inflammatory medicines (NSAIDs) like diclofenac or ibuprofen can cause kidney problems
  • Drugs that affect Apo-Perindopril: other antihypertensives like methyldopa, calcium entry blockers or beta blockers increase the antihypertensive effect
  • Drugs that are affected by Apo-Perindopril: lithium for mood disorders, antidiabetics like insulin

How should Apo-Perindopril be taken?

You should take your Apo-Perindopril tablets 4mg swallowed whole with a glass of water, once daily in the morning before a meal.  Your dose may be increased depending on what you are being treated for, how well your respond and your doctor’s recommendations.  Apo-Perindopril tablets 4mg helps improve your condition but does not cure it therefore, you should continue to take your Apo-Perindopril tablets 4mg for as long as your doctor recommends.  Apo-Perindopril tablets 4mg may take a few weeks to lower blood pressure and you should keep taking Apo-Perindopril tablets 4mg.

How long should you take Apo-Perindopril?

Apo-Perindopril tablets 4mg helps improve your condition but does not cure it therefore, you should continue to take your Apo-Perindopril tablets 4mg for as long as your doctor recommends.  Apo-Perindopril tablets 4mg may take a few weeks to lower blood pressure and you should keep taking Apo-Perindopril tablets 4mg.

Missed dose of Apo-Perindopril

If you miss a dose of Apo-Perindopril tablets 4mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Apo-Perindopril be stored?

You should store your Apo-Perindopril tablets 4mg below 25°C in a cool dry place. 

 

All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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