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Simlup 10mg 10 Tablets/Strip


Simlup 10mg 10 Tablets/Strip

Simlup 10mg (Simvastatin)

  Generic

This product has been discontinued, but we do have alternatives below.

Product Name
Simlup 10mg 10 Tablets/Strip
Also known as Zocor
Active Ingredient
Simvastatin
Manufacturer
Cipla Pharmaceuticals
Product Type
Hypolipidaemic (cholesterol-lowering), statin
Product expiry date we are currently shipping
Discontinued, no stock
Simlup 10mg tablets contain simvastatin 10mg a cholesterol-lowering medication that is used to treat high cholesterol by lowering high levels of cholesterol and triglycerides in the blood, which helps reduce risk of heart disease.

Simlup general information

What is Simlup used for?

Simlup 10mg is used to lower high levels of cholesterol (hypercholesterolaemia) and other fats (triglycerides) in the blood to reduce health risks associated with coronary heart disease (CHD), including heart attack and angina that can be caused by high cholesterol. Simlup 10mg is also used to prevent progression if you already have CHD, to reduce mortality; and also to treat people with diabetes or history of stroke, to reduce the need for surgery, and reduce the risk of stroke or peripheral vascular disease. There are usually no symptoms when you have high cholesterol, which may be due to lifestyle (high-fat diet and lack of exercise) or can be inherited.

How does Simlup work?

Simlup 10mg contains simvastatin which belongs to a group of cholesterol-lowing medications called statins. Cholesterol is needed by the body for many functions such as building cell membranes, producing certain hormones and transporting fat soluble vitamins around the body, however, if there is more cholesterol than the body needs, it becomes deposited in the artery walls where it can build up, blocking the arteries and increasing risk of heart disease. Simvastatin in Simlup 10 reduces the production of cholesterol in the liver, by inhibiting HMG-CoA reductase, an important enzyme involved in cholesterol synthesis. Simlup 10mg lowers levels of “bad” cholesterol (LDL) that can cause arteries to become hardened and blocked, and also increases levels of “good” cholesterol (HDL) that helps unblock hardened arteries. Simlup 10 mg only blocks cholesterol that is produced in the liver and has no effect on cholesterol that comes from fat in food, which is why a low-fat diet is important even when you are taking Simlup 10mg.

What Simlup doses are available?

Simlup tablets are available to order and buy online from Inhouse Pharmacy in doses of 10mg and 20mg as packs of 30, 60 or 90 tablets.

What does Simlup contain?

Simlup 10 contains the active ingredient simvastatin, which is a cholesterol-lowing medication belonging to the group of drugs called statins.

Lowering cholesterol with Simlup

Simlup 10mg contains the cholesterol-lowing statin medication simvastatin, which is used to lower levels of cholesterol and other fats (triglycerides) in the blood to reduce health risks associated with coronary heart disease (CHD), including heart attack and angina that can be caused by high cholesterol. Simvastatin in Simlup 10 reduces the production of cholesterol by the liver by inhibiting HMG-CoA reductase, an important enzyme involved in cholesterol synthesis. Simlup 10mg lowers levels of “bad” cholesterol (LDL) that can cause arteries to become hardened and blocked, and also increases levels of “good” cholesterol (HDL) that helps unblock hardened arteries. There are usually no symptoms when you have high cholesterol, which may be due to lifestyle (high-fat diet and lack of exercise) or can be inherited.

Treating high cholesterol (hypercholesterolaemia) with Simlup

Simlup tablets 10mg are used to treat high cholesterol (hypercholesterolaemia) which can increase risk of heart disease. Cholesterol is needed by the body for many functions such as building cell membranes, producing certain hormones and transporting fat soluble vitamins around the body, however, if there is more cholesterol than the body needs, it becomes deposited in the artery walls where it can build up, blocking the arteries and increasing risk of heart disease. Simlup 10 is used to lower high levels of cholesterol and other fats (triglycerides) in the blood, by reducing the production of cholesterol by the liver where it inhibits HMG-CoA reductase, an important enzyme involved in cholesterol synthesis. Simlup 10 mg only blocks cholesterol that is produced in the liver and has no effect on cholesterol that comes from fat in food, which is why a low-fat diet is important even when you are taking Simlup 10mg.

Effects of alcohol and grapefruit on Simlup

Alcohol if drunk is large quantities may increase the risk of liver problems when taking Simlup. Grapefruit juice in large quantities (more than one litre a day) can also increase risk of side effects as it increases the amount of Simlup that gets into your blood.

What are the side effects of Simlup?

Simlup is generally well tolerated but it is always possible that you may experience side effects. The more common side effect include: constipation, diarrhoea, abdominal pain, nausea, headache and dizziness. More serious side effects are less common and may include: muscle ache, tenderness or weakness, not caused by exercise, tingling in the hands or feet (paraesthesia), insomnia, fever, skin rash, itchiness, hives, painful, swollen joints, jaundice (yellowing of the skin and/or eyes), anaemia

When should Simlup not be used?

You should not use Simlup 10 if you:
  • are allergic or have a hypersensitivity to simvastatin or to any of the other ingredients of Simlup
  • have active liver disease
  • are pregnant or breast-feeding
  • are taking other medication that interacts with Simlup 10, including: macrolide antibiotics, such as clarithromycin, erythromycin, ritonavir for itraconazole and ketoconazole use to treat fungal infection, cyclosporin, used to suppress the immune system, cardiac glycosides like digoxin, antacids for indigestion, anticoagulants such as coumarin verapamil or diltiazem, medicines used to treat high blood pressure, angina, or other heart conditions, amiodarone, used to treat irregular heart beat

What medications interact with Simlup?

Several medications interact with Simlup tablets 10mg and should either not be taken while you are taking Simlup 10 or only after discussion and instruction from your doctor:
  • Drugs that cause a serious reaction or increase risk of side effects: macrolide antibiotics, such as clarithromycin, erythromycin, HIV protease inhibitor, such as ritonavir, itraconazole and ketoconazole use to treat fungal infection
  • Drugs that affect Simlup 10: other cholesterol lowering medication such as gemfibrozil, cyclosporin, used to suppress the immune system, verapamil or diltiazem, medicines used to treat high blood pressure, angina, or other heart conditions, amiodarone, used to treat irregular heart beat, anticoagulants such as warfarin
  • Drugs that are affected by Simlup 10: digoxin for heart failure; oral contaceptives

How should Simlup be taken?

You should take Simlup 10mg tablets with a glass of water once a day, preferably in the evening after your evening meal, although you can take Simlup with or without food. Simlup 10 is most effective at night when your body is resting and your liver is producing the most cholesterol. You should continue to take Simlup 10 for as long as recommended by your doctor, which may be for the rest of your life as Simlup 10 helps keep your cholesterol levels from being too high and if you stop taking Simlup, your cholesterol levels may rise again.

How long should you take Simlup?

Simlup 10 helps keep your cholesterol levels from being too high and if you stop taking Simlup, your cholesterol levels may rise again. Therefore you may need to take Simlup for the rest of your life, if recommended by your doctor.

Missed dose of Simlup

If you miss a dose of Simlup 10mg, take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Simlup be stored?

You should keep your Simlup 10mg tablets in the blister packs provided until use. Store Simlup 10 in a cool dry place where the temperature stays below 30°C.

All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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